Abstract
Objective To observe the effects of transplantation of cultured stromal vascular fraction (SVF) on infarcted myocardial tissue, cardiac function and the underlying mechanism. Design and methods Rats were randomly divided into 3 groups: sham-operated group, AMI control group and SVF transplantation group. SVF labeled with GFP after 3days or PBS was injected into the margins of infarcted tissue. 2weeks after transplantation, cardiac function was evaluated with homodynamic measurement. Fluorescence microscope was used to identify the survival of SVF cells in myocardium.
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