The Effects of Sperm Parameters on Pregnancy Results in Patients with Intra Uterine Insemination Using Recombinant FSH

Abstract

Aim of the study: Although there is an assisted reproductive technique commonly used in intrauterine insemination (IUI) assisted reproductive techniques, there is no definite consensus about sperm parameters affecting the possibility of pregnancy. The aim of this study is to evaluate the effects of motile sperm and morphology on pregnancy rates and determine optimal sperm parameters in patients undergoing IUI with rFSH ovulation induction (OI). Material and Methods: Between January 2009 and December 2010, Dr. Zekai Tahir Burak Women's Health Education and Research Hospital is a retrospective study involving 300 IUI cycles applied to 170 infertile patients in the infertility outpatient clinic. IUI cycles were divided into 10 million according to TPMSS (total progressive motile sperm count) after washing, ≤%4 and> 4% according to morphology, the effect of two parameters on pregnancy results. Findings: In our study, a total of 44 pregnancies were applied to 170 infertile patients with 300 cycles of IUI. Pregnancy was 14.6% according to the number of cycles and 25.8% according to the number of patients. While the pregnancy rate was 17.8% in the spouses of men with sperm morphology 4 4%, the pregnancy rate in the spouses of the patients with morphology> 4% was found 13.9% (p = 0.133). While the pregnancy rate of the spouses of men with TPMSS> 10 million was 14.8%, the pregnancy rate of the spouses of men with TPMSS <10 million was 13.3% (p = 0.668). Result: In our study, it was found that female age is important in the treatment of infertility, and pregnancies in infertility treatment usually occur in the first cycle. Morphology was found to be more important in terms of pregnancy, one of the sperm parameters. It was found that TPMSS alone was not related to pregnancy rates. It was determined that smoking does not affect pregnancy rates in women and it decreases pregnancy rates by disrupting morphology especially in men. Keywords: IUI, infertility, sperm parameters DOI: 10.7176/JSTR/6-05-08