Abstract
Although the effects of barbiturates on ovulation have been studied (Fraps and Case, 1953; Fraps and Conner, 1954; Bastian and Zarrow, 1952), the results are not conclusive. The drugs may block ovulation or stimulate it, or they may be completely ineffective. The effects of the barbiturates on oviposition have not heretofore been studied or reported, but those who have used nembutal (sodium pentobarbital) as an anesthetic on laying hens may have observed that the hen sometimes laid an egg prematurely while under the anesthesia. This has been observed frequently enough by one of us (P.D.S.) to suggest the need for detailed studies on the effects of nembutal on oviposition, which is the objective of this experiment.We studied the effects of nembutal injected intravenously at an anesthetizing level (30 mgs./kg.) on oviposition in hens with a hard shell egg in uterus, 1 to 6 hours prior to estimated laying time, …
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