Abstract

CFF thresholds were determined in groups of smokers and non-smokers when nicotine was administered (a) through smoking a cigarette, (b) orally. It was found that the CFF threshold was raised after the administration of nicotine orally, and also after smoking one cigarette; however there was no change after smoking for non-smokers (presumably because they fail to inhale) or for smokers who had not abstained beforehand. The experiment supports the hypothesis that nicotine is a stimulant drug.

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