Abstract

全身麻酔下にレミフェンタニル(RF)とフェンタニル(F)を約3ng/mLの効果部位濃度で維持し,血圧低下・徐脈作用を比較した.80名を対象とし,無作為にRF群,F群の2群に分けた.心拍数(HR),収縮期血圧(SBP),拡張期血圧(DBP),平均血圧(MBP)の最大低下率(%)は,RFではそれぞれ20.3±15.9,39.5±12.8,35.0±12.2,35.7±12.1%,Fでは19.2±15.8,34.9±11.8,28.4±11.7,29.7±11.1%(M±SD)であった.除脂肪体重,年齢,フェニレフリン,アトロピンの影響を精査した結果,RF群とF群で有意差はないと考えられた.

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