The Effects of Regulator of G-Protein Signaling 2 (RGS2) on Depression-Like Behavior in Female California Mice

Alexia Williams,Catherine Pena,Abigail Laman-Maharg,Evelyn Ordonez-Sanchez,Christine Xu,Stephanie Ramos-Maciel,Rebecca Hao,Sae Yokoyama,Benoit Labonte,Melody Wu,Jessica Tollkuhn,Venetia Zachariou,Eric Nestler,Brian Trainor

doi:10.1016/j.biopsych.2021.02.202

The Effects of Regulator of G-Protein Signaling 2 (RGS2) on Depression-Like Behavior in Female California Mice

Alexia Williams, Catherine Pena + Show 12 more

https://doi.org/10.1016/j.biopsych.2021.02.202

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Journal: Biological psychiatry

Publication Date: Apr 27, 2021

Affiliation: University of California, Davis, Princeton University, Temple University, Cold Spring Harbor Laboratory, Icahn School of Medicine at Mount Sinai

#Regulator Of G-protein Signaling 2 #Female California Mice + Show 8 more

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Abstract

Stressful experiences are a well-known risk factor for the development of psychiatric disorders such as depression (MDD). Although many pharmaceutical therapies have been developed, over half of individuals that seek treatment do not respond positively, indicating a dire need for new treatments and thus new molecular targets.

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