The effects of premarital medical examination on primary prevention of birth defects

Abstract

Objective To explore the associated factors of premarital medical examination (PME) and investigate its effects on primary prevention of birth defects. Methods 300 pregnant women enrolled in the out-patient department of Obstetrics and Gynecology Hospital Affiliated to Fudan University from September 29, 2006 to November 1, 2006 were divided into 2 groups according to performing PME or not. A questionnaire was used to survey PME, basic characteristics of pregnant women, cognition of prevention of birth defects, and its influences on preconceptional counseling. Results The total rate of PME was 42.7%, the difference of the rate of PME was significantly lower in Shanghai native men(35.1%) than that in foreigners from other provinces(50.7%) and foreigners from other countries(43.7%). Women with middle level of education and income had lowest rate of PME, compared with high and low level of education and income. The rate of PME in medical staff was lower than the average rate. The rates of preconceptive supplement of folic acid in 2 groups were similar. However, preconceptional counseling in the right way in women with PME was higher than those women without PME(14.8% and 4.7%) (P<0.05). Conclusion The role of PME in prevention of birth defects is restricted and it should be innovated in China. Key words: premarital medical examination(PME); preconceptional counseling; birth defects; primary prevention