Abstract
BackgroundWith the exception of sexual functioning and weight, social and behavioural effects of postmenopausal hormone therapy (HT) have not been reported from trials. This paper reports such results from the EPHT-trial in Estonia.MethodsA randomized trial, with a blind and non-blind sub-trial in Estonia. From 1999–2001, 1778 women were recruited. The mean follow-up was 3.6 years. Women's experiences were asked in the first and final study year by mailed questionnaires (74 and 81% response rates). Comparisons of the groups were made by cross-tabulation and logistic regression, adjusting for age.ResultsThere were no differences between the HT and non-HT groups in regard to being employed, the extent of social involvement or marital status or opinions on aging. There was no difference in the frequency of free-time exercise, or overweight. Some of the indicators suggested less sexual inactivity, but the differences were small.ConclusionIn a trial setting, postmenopausal hormone therapy did not influence work or social involvement or health behaviour.Trial registrationISRCTN35338757
Highlights
With the exception of sexual functioning and weight, social and behavioural effects of postmenopausal hormone therapy (HT) have not been reported from trials. This paper reports such results from the EPHT-trial in Estonia
There were no differences between the HT and non-HT groups in regard to being employed, the extent of social involvement or marital status or opinions on aging
There was no difference in the frequency of free-time exercise, or overweight
Summary
With the exception of sexual functioning and weight, social and behavioural effects of postmenopausal hormone therapy (HT) have not been reported from trials. With the exception of sexual functioning and weight (as a proxy for health habits), non-health benefits, such as better work capacity and social involvement have not been studied in trials, devoid of selection bias, and the data of surveys are limited. Surveys of both physicians and women have focused on the level of HT use and the medical reasons for use; non-.
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
