Abstract
The toxicity of butylbenzyl phthalate(BBP), di- n-heptyl phthalate(DNHP) and n-butyl lauryl phthalate(BLP) to fibroblasts from newborn rat cerebellum in primary culture was significant at concentrations of 7.0, 2.7, and 5.0 · 10 −4 M, respectively. The toxicity of di-methoxyethyl phthalate(DMEP), butyl phthalyl butyl glycolate(BPBG), di- n-octyl phthalate(DNOP), and di-(2-ethylhexyl) phthalate(DEHP) was not significant. Phthalic acid and potassium hydrogen phthalate (K-phthalate) were the least toxic to fibroblasts. Comparison of the toxicity to fibroblasts of five phthalate esters of normal series showed that dimethyl phthalate(DMP) < diethyl phthalate-(DEP) < di- n-butyl phthalate(DNBP) > DNHP > DNOP.
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