Abstract
Electrical stimulation of the central end of the cut vagus of the rabbit produced 2 types of blood-pressure response, depending on the frequency used: stimulation at low frequencies (<20/sec) or at high rates (> 100/sec) lowered blood pressure, whereas intermediate frequencies (50–100/sec) raised blood pressure. Small doses of pentobarbitone converted the high-frequency depressor response into a pressure rise, but did not alter qualitatively the effects of stimulation at low or intermediate frequencies. Cerebellectomy reduced the amplitude of all blood-pressure changes, evoked by stimulation of the central end of the cut vagus, but did not change their direction. Thus, blood-pressure changes evoked by stimulation of the central end of the cut vagus of the rabbit behave differently from those evoked by sciatic stimulation. The central pathways involved in these blood-pressure changes are discussed in the light of the present observations.
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