Abstract
Step-down passive avoidance acquisition and 24 h retention performance were examined in adult rats given daily doses of either 0, 1, or 5 mg kg cadmium (Cd) (as CdCl 2) via the diet. Results indicated that subjects exposed to the 5 mg kg Cd diet were less likely to step off a safe platform onto an electrified grid floor than controls. The 1 mg kg subjects did not differ from controls on this acquisition task. None of the groups showed differential performances on a retention test administered 24 h after acquisition training. These results are discussed in terms of recent claims that Cd exposure enhances emotional reactivity in animals.
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