Abstract
The benefit of the nutritional support provided to patients with colorectal cancer who have undergone the planned resection of the colon in relation to the laboratory markers of nutrition was examined. And it is currently being discussed, that pre-operative optimization of nutritional status reduces the incidence of post-operative complications in cancer patients and regulates selected laboratory parameters. This was a retrospective study where the treatment group (n = 52) received the enteral nutritional support 21 days prior to the scheduled surgery and the other group was formed of patients without preoperative enteral nutrition (n = 52). Laboratory parameters (CRP, leukocytes, albumin, total proteins) were monitored for at least one month before the planned surgery and just before the operation, and the effect of supplemental enteral nutrition on selected laboratory parameters between these two groups was compared. In a group of patients with enteral nutrition, serum albumin levels increased significantly, while CRP was significantly reduced during preoperative enteral nutrition (albumin S-ALB from 35.42 to 37.48, p = 0.0008, C reactive protein from 26.5 to 14.092, p = 0.0007). Nutritional support 21 days prior to surgery in oncological patients resulted in an improvement in laboratory parameters compared to the group of patients without nutritional enteric support. Malnutrition in patients who are candidates for major surgical intervention is a risk factor for postoperative morbidity and mortality. However, further studies are required to verify the effectiveness of this early nutritional intervention on medium and long-term clinical parameters in different types of cancer.
Highlights
Cancer of the colon and rectum is one of the most commonly diagnosed cancers in the world (Torre et al, 2015)
In a group of patients with enteral nutrition, serum albumin levels increased significantly, while C-reactive protein (CRP) was significantly reduced during preoperative enteral nutrition
We examine in our study, whether the administration of Nutridrink compact rises the level of albumin and lowers the level of C-reactive protein in patients with colon cancer before the planned surgery
Summary
Cancer of the colon and rectum is one of the most commonly diagnosed cancers in the world (Torre et al, 2015). It is important to provide nutritional support administered through enteral nutrition or parenteral nutrition (Chow et al, 2020). These approaches are accompanied by concerns with increased complications and costs. Enteral nutrition can be the preferred form due to its lower costs, less complications, and improved results (Altintas et al, 2011). We examine in our study, whether the administration of Nutridrink compact rises the level of albumin and lowers the level of C-reactive protein in patients with colon cancer before the planned surgery
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