Abstract

<h2>Summary</h2> In 50 normal CSF samples, no thrombin, fibinogen, prothrombin, proconvertin, proaccelerin, antihemophilic globulin or thromboplastin activity was found. These samples had no effects different from those produced by artificial control solutions on the coagulation time of a thrombin-fibrinogen system, and they demonsrated no fibrinolytic activity. In addition, they had no effect on chick fibroblast growth. There is no idication from these results that CSF specifically interferes with the healing of ruptured intracranial aneurysms.

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