Abstract
In cortical bone, the effect of absorption in the solid matrix on ultrasound scattering and propagation is not well understood, and for absorption, it is not easily incorporated into simulations and is difficult to measure independently from scattering attenuation. In this study, finite-difference time-domain simulations were conducted in maps derived from scanning acoustic microscopy images of human femur cross-sections. These maps were modified by controlling pore density (fixed at 10 pores/mm2) and diameter distribution (ranging between 30 and 100 μm). Eight nominal absorption values, ranging from 0 to 100 dB/cm, were attributed to the solid matrix. Absorption in the pores was set to 0.01 dB/cm. Propagation of ultrasound pulses centered at 8 MHz was simulated in both backscattering and through-transmission configurations. The scattering, absorption, and overall attenuation extinction lengths were obtained. T-tests demonstrated that varying the absorption significantly impacts the extinction lengths for scattering, overall attenuation, and absorption. The differences in values for the scattering, attenuation, and absorption extinction lengths when absorption varied from 20 to 40 dB/cm are statistically significant (respective p-values: 9.1 × 10−14, 3.3 × 10−5, and 8.8 × 10−5). It was also demonstrated that attenuation due to scattering dominates overall attenuation at low-nominal absorption values, whereas the converse is true at higher absorption values.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.