Abstract
Four experiments investigated the effects of the opioid antagonist naloxone hydrochloride on learning and expression of preferences for flavors paired with calories from dextrose or ethanol. Experiments 1 through 3 showed that naloxone eliminated a dextrose-paired flavor preference in two-bottle and one-bottle tests. When naloxone was paired with flavored dextrose in conditioning trials, no preference for the naloxone-paired flavor over the saccharin-paired flavor emerged. Naloxone also eliminated the preference for an ethanol-paired flavor over a saccharin-paired flavor in postconditioning tests.
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