Abstract
1.1. Quantitative studies of cerebral blood flow, cerebral oxygen metabolism, cerebral vascular resistance, mean arterial blood pressure, respiratory quotient of the brain, and the blood gases were made upon 7 normal and 12 toxemic pregnant women before and after the administration of morphine sulfate.2.2. There was no statistically significant change brought about upon these functions by morphine, although there was some lowering of blood pressure and cerebral vascular resistance and increase in cerebral blood flow.3.3. The effects upon the brain of morphine were compared with those brought about by barbiturates.4.4. It was concluded that morphine exerts a more physiologic effect upon the cerebrum than the intravenously administered barbiturates.
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