Abstract

To the Editor:— editorial, The Effects of Mineral Oil, in the October 25 issue ofThe Journal, page 512, caused me to react with mixed emotions, the dominant one that of satisfaction and vindication. In 1913, 1914 and 1915 Weighart, Von Oefele and I conducted many animal experiments with mineral oil. We fed them oil and later recovered it in appreciable quantities from the subcutaneous connective tissue and fat, proving that it was absorbed from the intestinal tract. That finding in addition 'o the resulting effect on the sulfur metabolism, we felt might favor the growth of cancers. I read an abstract of our work at the summer meeting of the American Pharmaceutical Association at Atlantic City, N. J., in 1916. They never published the paper in their journal. In my opinion, prescribing mineral oil for constipation not only is stupid therapy but also could be dangerous.

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