Abstract
The micromycetes of the Aspergillus genus were screened for the evaluation of their capacity to secrete extracellular proteolytic enzymes effecting proteins of the human hemostatic system. Aspergillus extracellular proteases were found to cleave chromogenic peptide substrates specific for the hemostatic proteins, as well as to activate some proenzymes (protein C, factor X, and prothrombin). The activation of human blood plasma X-factor by micromycete extracellular proteases was first shown.
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