Abstract
The effects of SC injections of methionine-enkephalin (Met 1−5-Enk) and its N-terminal and C-terminal fragments upon the duration of the dursal immobility response (DIR) over a 60-min time course were investigated. Experiment 1 analyzed the effects of various dosages (0.00–100.0 μg/kg) on DIR resulting in a potentiation of the duration in a dose-time course function. The effects of various fragments of Met 1−5-Enk (10.0 μg/kg) from the N-terminal in Experiment 2 and from the C-terminal in Experiment 3 on the DIR resulted in the potentiation of the duration with the Met 2−5-Enk and Met 1−3-Enk fragments. All other fragments were not significant. The results were discussed in reference to the processing and metabolism of Met 1−5-Enk.
Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
