Abstract

Before mating with males of the A2G or CBA inbred strains of mice, C57BL females were immunized against either the paternal strain antigens (allogeneic) or Peromyscus species antigens (xenogeneic). Evidence is presented which indicates that, contrary to earlier reports, pre-immunization has no effect on placental size, but may reduce foetal weight and litter size. The r\l=o^\lesof specific immunity and non-specific `stress' are discussed.

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