Abstract

The Effects of Maternal Dietary Supplementation of Cholecalciferol (Vitamin D3) and 25(OH)D3 on Sow and Progeny Performance

Highlights

  • Vitamin D3 plays a major role in regulating Ca and P absorption and metabolism in animals, especially for bone

  • A total of 69 sows (DNA Line 200 × 400) and their progeny were used to determine if feeding a combination of vitamin D3 (Rovimix D3, 500,000 IU/g; DSM Nutritional Products, Parsippany, NJ) and 25(OH)D3 (Hy-D, DSM Nutritional Products, Parsippany, NJ) influences neonatal and sow vitamin D3 status, muscle fiber morphometrics and development of the piglets, and subsequent growth performance to market

  • Within 3 days of breeding, sows were allotted to 1 of 3 dietary treatments fortified with 680 IU/lb vitamin D3 (CON), 227 IU/lb vitamin D3 + 11.3 μg/lb 25(OH)D3 (DL), or 680 IU/lb vitamin D3 + 22.7 μg/lb 25(OH)D3 (DH)

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Summary

Introduction

Vitamin D3 plays a major role in regulating Ca and P absorption and metabolism in animals, especially for bone. This is important for the growth and maintenance of a functional skeleton to sustain health and improve welfare and longevity. After ingestion and absorption of vitamin D3, the 25th carbon of vitamin D3 is hydroxylated in the liver to form calcidiol (25(OH)D3). This metabolite is transported through the blood to the kidney where additional hydroxylation occurs to form different metabolites of vitamin D3, including 24,25(OH)2D3 and the active hormone form of vitamin D3 calcitriol (1,25(OH)2D3), each with its own function in the body. The level of calcidiol found in blood serum is considered a good indicator of an animal’s vitamin D3 status (i.e. deficient, adequate, toxic).

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