Abstract

Background and Aims: Apoptosis, that occurs after hypoxia/reoxygenation (H/R), has an important role in the pathogenesis of necrotizing enterocolitis (NEC) which is a major cause of morbidity and mortality in premature infants. Telomerase activity, showing the regenaration capacity, may also be important in the recovery process. We aimed to see the effects of insulin-like growth factor-1 (IGF) and erithropoetin (EPO) on apoptosis and telomerase activity in a H/R model.

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