Abstract
Relatively large quantities of decidual tissue closely resembling the maternal placenta have been produced in rabbits by aspiration of early conceptuses. The effect of this decidual tissue on luteal maintenance has been evaluated and compared with the condition resulting from hysterectomy during early pregnancy or pseudopregnancy. Luteal maintenance was assessed by luteal weights and histology and levels of progesterone and 20α-hydroxy-4-pregnen-3-one in ovarian venous blood. Neither hysterectomy nor decidual induction resulted in a condition of luteal maintenance equivalent to pregnancy, but both treatments sustained corpora lutea beyond the normal duration of pseudopregnancy. Hysterectomy during early pregnancy was at least as successful in this regard as was uterine removal in pseudopregnancy. (Endocrinology 93: 348, 1973)
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