The effects of hand preference and sex on right-left asymmetry in dorsal digit lengths among adults and children

Abstract

BackgroundRight-hand preference is related to stronger right-directional asymmetry in the length of proximal upper-limb bones, although the relationships of hand preference with directional asymmetry in phalangeal bone lengths are not known. Furthermore, dorsal digit length is an easy-to-measure, faithful proxy of X-rayed phalangeal bone length (which is costly and difficult to measure). AimTo study the effects of hand preference, sex, and age on right-left (R-L) asymmetry in dorsal digit lengths. MethodsWe measured all dorsal digit lengths (except the thumb) in comparable numbers of left-handers and right-handers in samples of adults (N = 151, age: M = 22.6 years, SD = 3.3) and children (N = 65, age: M = 5.0 years, SD = 1.0). ResultsRight-handers and adults had stronger right-directional asymmetry in digit lengths than left-handers and children. A Bayesian analysis yielded an ‘extremely strong likelihood’ of no sex differences in the R-L asymmetry of dorsal digit lengths 2 and 4. ConclusionsThe effects of hand preference, sex, and age on R-L asymmetry appear to be similar for phalangeal bone length and other (proximal) upper-limb bone lengths. Two distinct biologic mechanisms (i.e., a general right-directional asymmetry mechanism and a handedness-related directional asymmetry mechanism) may contribute to observed R-L asymmetry in limbs. Fingertip fat and bone digit length do not seem to contribute to sex differences in the R-L asymmetry (Dr-l) of the widely studied second-to-fourth digit ratio (2D:4D).