Abstract
BackgroundGreen tea is well known for its anti oxidant and anti inflammatory properties. In this study we sought to analyze the protective effects of prolonged consumption of green tea on the adrenal cortex of aged rats.Material and MethodsThirty female albino rats were divided into three groups of ten animals each. Group I: the control group, 6 months‐old rats. Group II: aged, 18‐month‐old rats. Group III: Green tea treated rats, which included 12 month‐old rats that consumed green tea at a dose of 300 mg/Kg body weight orally by a gastric tube for a duration of 6 months. The adrenal gland was obtained from the three assigned groups and processed for light microscopic evaluation.ResultsIn the aged rats, the adrenal cortex appeared to have some degenerative changes in the three layers of the adrenal cortex, namely zona glomerulosa, fasciculata, and reticularis. The changes ranged from increase in the vacuolizations of the cytoplasm of the cells, and darkening of their nuclei. With the administration of green tea, there was improvement of some of these histological changes.ConclusionAging resulted in some degenerative changes in the rat adrenal cortex which were ameliorated by the administration of green tea.
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