Abstract
This study mainly concentrates on the discussion of the relationship between FOXP2 gene and language functional articulation disorder. The chil dren of functional articulation disorder are select ed, the normal healthy subjects in the corresponding pe riod served as the controls, by contrasting with fi ve polymorphic sites in FOXP2 gene to have a correlati ve study on human genes and language acquisition with the language barriers as main characteristics, in order to further prove the significance of FOXP 2 gene in cultivating language and speech.
Highlights
There only one thing in the world can be used for communication is creatures
This study mainly concentrates on the discussion of the relationship between Forkhead box p2 (FOXP2) gene and language functional articulation disorder
The children of functional articulation disorder are selected, the normal healthy subjects in the corresponding period served as the controls, by contrasting with five polymorphic sites in FOXP2 gene to have a correlative study on human genes and language acquisition with the language barriers as main characteristics, in order to further prove the significance of FOXP2 gene in cultivating language and speech
Summary
There only one thing in the world can be used for communication is creatures. Scientists found that in many human genes, FOXP2 gene enables people to speak; without this gene, people civilization and language won’t have chance to go further. In the past several hundred thousand years, the change of FOXP2 is the root cause of promoting mankind to evolve towards different routes with other lives Once this gene has been destroyed, it will lead to rare disorders of language, which may bring serious problems in language applications. The mutation of Exon 14 G/A in the FOXP2 gene leads to severe language and speech disorders of illness members in “KE” family, which mainly shows developmental verbal apraxia, comprehension and expression disorders for written and spoken language as well as orofacial fine motor disorders and so on. Lai et al (2000) found out a boy irrelevant with “KE” family called “CS” boy, which has a similar language and speech disorders; his introne between exon 3b and 4 in FOXP2 gene occurs breakage and translocation with No. chromosome ((5:7) (q22; q31.2)). FOXP2 gene as rs923875, rs2396722, rsl852469, rs17137124 and rs51456031 by comparing allele and genotype frequency in 150 children of functional articulation disorders and 140 healthy subjects and haplotype analysis is performed according to linkage imbalanced results, aiming at discussing the correlation of FOXP2 gene and functional articulation disorders
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