Abstract
In recent times, different plant extracts have been reported to exert fertility enhancing effects. Carica papaya fruit is known for its use in preparation of herbal remedies. The aim of this study is to investigate the effects of Carica papaya on the reproductive system of female Wistar rats. Sixteen (16) female Wistar rats with regular oestrous cycle were used for this study. Animals were grouped into four (4) groups (control, low dose, middle dose, and high dose) of 4 animals each. Carica papaya fruit extract was administered for 14 days while monitoring the oestrous cycle. Twenty hours after the last administration, animals were sacrificed, and blood samples taken. Blood samples were collected for hormonal assay. Data obtained was expressed as Mean ± standard deviation, values were considered statistically significant when P ≤ 0.05. Phytochemical analysis of premature Carica papaya fruit revealed the presence of alkaloids, terpenes, sterols and terpenoids were heavily present. Estrous cycle was not altered. Serum FSH and LH increased. The extract is likely to possess fertility enhancing properties.
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