Abstract
Home parenteral nutrition (HPN) is a life-sustaining therapy for individuals with intestinal failure. It refers to the intravenous infusion of macronutrients, micronutrients, fluids and electrolytes.1 Routinely used HPN solutions contain different quantities of these components. Consequently, each HPN solution may have different impacts on metabolism, inflammation and oxidative stress. Long-term use of HPN can lead to a number of adverse health outcomes including the development of metabolic bone disease, intestinal failure associated liver disease and poor quality of life2 but whether, and how, the composition of HPN solutions contributes to these health sequelae is poorly understood.
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