Abstract
Twenty young adult male rats were divided into two groups of ten rats each and fed either a powder or pellet diet of identical content for a thirty day experimental period. One hour prior to sacrifice, each rat was given an intraperitoneal injection of 0.5uc of tritiated thymidine per gram of body weight. After sacrifice, the maxillae were dissected out and prepared for autoradiographic and histologic study.Proliferative cellular activity was determined in the periodontal tissues of the maxillary first molars. Significantly higher activity was noted in the crestal epithelium and in the fibroblasts at the interradicular septum of the pellet fed rats when compared to powder fed animals. These elevated values may reflect tissue responses to the coarser consistency of the pellets.
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