The effects of diets containing sucrose, glucose or fructose on experimental dental caries in two strains of rats

Abstract

Fructose, glucose and sucrose were compared at a level of 33 per cent in the diet of two strains of rats. In three of the four sets of results sucrose produced more caries than glucose or fructose. There was no consistent difference in cariogenicity between glucose and fructose. The two strains of rats differed in their susceptibility to caries on high-sugar diets, and caging rats from both strains together in one experiment did not appear to alter their relative susceptibility to caries.