Abstract
AbstractThe pathological effects of gossypol in animals and the effects of protein quality and quantity on its toxicity are described. The method used for the isolation of gossypol from the liver of gossypol‐intoxicated pigs and its identification are presented. Wide distribution of gossypol in swine is shown by determining the free and bound gossypol in the various organs. The levels of iron necessary to overcome toxicity and to lower its accumulation in pigs were investigated. Effects of copper, zinc, manganese and iron, alone and in combination, on the gains and the accumulation of gossypol in the liver of rats were studied. Iron was definitely the most effective detoxifying agent.
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