Abstract
Synthetic glucocorticoid dexamethasone decreased locomotor activity of neonatal rats 120 h after administration. Behavioral changes were associated with an increase in the content of active caspase-3 in the cerebellum. We found that expression of this apoptotic protease was similar to the control value when dexamethasone action was combined to hypoxic treatment to rats; however, the locomotor activity decreased to the hormone action did not recovered. We found that proapoptotic action of dexamethasone was blocked by hypoxic treatment; however, it was not sufficient for prevention of the effect of hormone on behavior.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
