Abstract

The effects of 33 steroids on the growth of Neurospora crassa were examined. Of these, deoxycorticosterone (DOC) showed a marked and relatively specific inhibitory effect. It has also been shown that DOC inhibits the uptake of sugars, amino acids, and rubidium. The results obtained suggest the possibility that the action of DOC is directed against certain permeability processes of the Neurospora cell. The implications of these observations have been discussed.

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