Abstract
The effects of large doses of human chorionic gonadotropin administered for long periods of time were studied in a case of Klinefelter's syndrome exhibiting the Barr nuclear chromatin body as in the female. There was an evident relationship between the histologic changes in the testes (Leydig cell hyperplasia and signs of active secretion) and the increase in the urinary excretion of 17-KS and estrogens. The mammary tissue showed an increase in the number of ducts with papillary projections lined by multilayered hyperplastic epithelium. Urinary gonadotropin excretion remained unchanged.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: The Journal of clinical endocrinology and metabolism
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
