THE EFFECTS OF BMI ON PROGESTERONE LEVELS AND PREGNANCY OUTCOMES FROM CRYOPRESERVED BLASTOCYST TRANSFER CYCLES

Abstract

Obese women have decreased reproductive outcomes due to impaired oocyte quality, uterine environment, and embryonic development and have significantly lower live birth rates (LBR) following IVF compared to normal weight women (1). Obesity affects pharmacokinetics as shown by lower serum human chorionic gonadotropin (hCG) measured post hCG trigger (2). A study on frozen embryo transfer (FET) cycles found that increased body weight significantly decreased serum progesterone (P4) levels but did not affect LBR (3).