Abstract
The present study aimed to evaluate the role of bioactive components in Solanum nigrum fruit, its phytochemical screening, and in vivo antioxidant potential against liver injury. The HPLC analysis of an ethanolic extract of Solanum nigrum fruit revealed the presence of bioactive components that showed its significant in vitro antioxidant activity. Moreover, The Sprague Dawley rats were divided into four groups for in vivo analysis: G1 (negative control), G2 (positive control), G3 (rats receiving standard drug), and G4 (rats receiving Solanum nigrum fruit extract). The Solanum nigrum fruit reduced the level of liver enzymes, and bilirubin. An opposite trend was seen in the case of albumin, catalase, creatinine, and superoxide dismutase. Histology slides also showed the normal cell structure of hepatocytes. Conclusively, Solanum nigrum fruit bioactive components have the ability to reduce oxidative stress.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
