The Effects of Acute Mobile Phone Radiation on the Anxiety Level of Male Rats

Abstract

Objectives: Despite two decades of using mobile phone, the biological effects of electromagnetic radiation remain controversial. The study was conducted to determine the effect of mobile phone waves on anxiety-like behaviors in male rats. Methods: A total number of 80 male naive rats were, randomly, divided into eight groups (Control, 900, 1 800, and 2 100 MHz exposure). The acute and chronic effects of mobile phone radiation on the anxiety profile was compared considering a 45-min session and seven sessions of radiation (45 min/day) using the elevated plus-maze (EPM) in rats. The number of rats entering the open and closed arms and their duration of stay in each of the arms were assessed. To estimate the oxidative stress, Superoxide Dismutase level in the blood serum was evaluated. Results: The results obtained in the EPM showed no significant differences among the groups after acute exposure to mobile phone radiation (P > 0.05). No significant differences were observed among the groups in terms of their serum superoxide dismutase level (P > 0.05). Conclusions: Short time mobile phone radiation had no effect on anxiety-like behaviors and serum enzyme activity; this may be due to low tissue irritation during acute exposure to mobile phone waves.