Abstract
Summary— The sebum excretion rate and chemical composition of sebum from the foreheads of 4 young men with acne vulgaris were changed markedly when a 2-naphthol paste was applied to other skin sites. The excretion rate, free fatty acid content and wax ester content fell but the triglyceride content increased. Recurrence of acne on stopping treatment was associated with an increase in wax ester content and a decrease in triglyceride content but little change in excretion rate and free fatty acid content.
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