The Effectiveness of Two Species of Lactic Acid Bacteria Lactobacillus casei and Lb. acidophilus in Some Biological Parameters of Rats Exposed to the Bisphenol-A

Abstract

The study was conducted in order to determine the concentration of Bisphenol-A in some samples of canned meats in Iraqi markets and the effect of oral administration with 5 and 10 µg/kg from Bisphenol A with drinking water on growth and biochemical parameters in laboratory rats after 21 days. The results showed the presence of Bisphenol A in samples of chicken meat Arizan at 1.04 µg/kg, in beef marked Nutrition at 2.52 µg/kg, and in fish meat marked Founty at 4.65 µg/kg. while when adding the Bisphenol, A at 5 and 10 µg/kg with drinking water caused in significant reduction (P<0.05) in the body weight of animals with increasing the concentration of those Bisphenol A. While the values total protein and albumin were not affected by the increased from this material. The values of the globulin, uric acid, creatinine and urea, further the activity of each enzyme ALP, ALT and AST were significantly increased with increased of Bisphenol A concentrations, It also found that the addition of Bisphenol A led to increase the total counts of pathogenic bacteria and decreased the total counts of lactic acid bacteria in animals intestinal. The addition of two types of lactic acid bacteria Lb. casei and Lb. acidophilus led to decreasing the negative effect of Bisphenol A on the values of all the parameters determined.