The effectiveness of treatment of chronic generalized periodontitis with the use of substitution therapy in women with hormonal status disorders

Abstract

Relevance. In clinical observations, a combination of somatic pathology with various forms of periodontal tissue diseases has long been established. Hormonal status is of particular interest in this direction, since hormonal failure causes disturbances in the hormonal background of a person.Goal. The aim is to increase the effectiveness of treatment of women with chronic generalized periodontitis on the background of hormonal imbalance by correcting the receptor status of the gingival epithelium.Materials and methods of research. The research methodology provided for the integration of clinical, laboratory, histological and immunohistochemical methods. To realize the purpose of the study, a systematic approach was used, which was based on the analysis of the content of interrelated sources of primary information. The object of the study were women aged 18 to 59 years, who were assessed for periodontal status against the background of gynecological pathology and hormonal imbalance with the use of substitution therapy.Conclusions. The inclusion in the complex treatment of periodontal tissue diseases of drugs with receptor-modulating and anti-inflammatory effect normalizes the work of the receptor apparatus of the gingival epithelium, which increases the effectiveness of the treatment of periodontal pathology.