Abstract

Objective To assess the effectiveness of traditional Chinese Medicine(TCM) syndrome differentiation treatment for diabetic nephropathy in elderly patients. Methods A total of 96 elderly patients with diabetic nephropathy admitted to our hospital from January 2015 to December 2017 were recruited and divided into a regular care group(n=48)and a TCM group(n=48). Both groups received conventional treatment, with TCM syndrome differentiation treatment added to the TCM group.The effectiveness of the treatment modalities was compared. Results In the regular care group, significant effectiveness was observed in 12 patients, effectiveness in 24 patients, and ineffectiveness in 12 patients, with a total effectiveness rate of 75%.In the TCM group, significant effectiveness was seen in 18 patients, effectiveness in 27, and ineffectiveness 3, with a total effectiveness rate of 93%.The total effectiveness rate of the TCM group was higher than that of the regular care group(χ2=6.400, P=0.011). After treatment, fasting blood glucose, 2 h postprandial blood glucose, urea nitrogen, creatinine, and 24 h urine protein in the TCM group were significantly lower than in the regular care group and than pre-treatment levels(P<0.05). Conclusions TCM differentiation can not only significantly improve the treatment effectiveness in elderly patients with diabetic nephropathy, but also relieve the clinical symptoms. Key words: Diabetic nephropathy; TCM syndrome differentiation; Clinical efficacy

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