Abstract
The effectiveness of remineralizing agents in reducing dentine permeability by tubule occlusion using fluid filtration device functioning at 100 cmH2O (1.4 psi) pressure and SEM/EDX analysis were evaluated and compared. Seventy (n = 70) dentine discs of 1±0.2 mm width were prepared from sound permanent human molars. Fifty (n = 50) dentine discs were randomly divided into 5 groups (n = 10): Group 1: GC Tooth Mousse Plus (Recaldent GC Corporation Tokyo, Japan), Group 2: Clinpro™ White Varnish (3M ESPE, USA), Group 3: Duraphat® Varnish (Pharbil Waltrop GmbH, Germany), Group 4: Colgate Sensitive Pro-Relief™ dentifrice (Colgate Palmolive, Thailand), and Group 5: Biodentine™ (Septodont/UK). Dentine permeability was measured after treatment application at 10 minutes, artificial saliva immersion at 7 days, and citric acid challenge for 3 minutes. Data were analyzed by two-way repeated measures ANOVA. Dentine specimens (n = 20) were used for SEM/EDX analyses to obtain qualitative results on dentine morphology and surface deposits. Each treatment agent significantly reduced dentine permeability immediately after treatment application and created precipitates on treated dentine surfaces. All agents increased permeability values after 7 days of artificial saliva immersion except Clinpro White Varnish and Biodentine. Clinpro White Varnish exhibited significant resistance to acid challenge compared to others. Colgate Sensitive Pro-Relief dentifrice has a dual mechanism of action in reducing the dentine sensitivity.
Highlights
The dentine sensitivity (DS) is a common dilemma in adults’ population with a prevalence ranging from 8 to 57% [1] and is ascribed in routine dental practice perceived generally from the second to sixth decade of life [2]
The dentine discs were prepared from caries-free human molars extracted for surgical reasons obtained from clinics and multihealth centers under a protocol set by the Ethics Committee of the Faculty of Dentistry, University of Malaya (UM), before the commencement of the study
All treatments showed a decrease in dentine permeability
Summary
The dentine sensitivity (DS) is a common dilemma in adults’ population with a prevalence ranging from 8 to 57% [1] and is ascribed in routine dental practice perceived generally from the second to sixth decade of life [2]. It has a multifactorial etiology and is described clinically as an acute pain caused by excitation of A delta nerve fibers connected to exposed dentine and its tubules due to chemical, thermal, osmotic, evaporative, or tactile stimulation [3]. It has been proposed that management should be targeted on not just by achieving the tubule impermeability by its occlusion and by monitoring the neural components within the pulp to stifle the peripheral stimulatory effects [7]
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