Abstract

Almost all patients receiving hepatitis C antiviral therapy will experience some treatment-related adverse effects. Emotional distress and fatigue can lead to early treatment discontinuation. Close monitoring is crucial throughout treatment. The nurses can promote adherence by counseling patients on the recognition and management of treatment- related adverse effects. The purpose of the study was to evaluate the effectiveness of nursing intervention program on emotional distress, self-efficacy and liver enzymes among hepatitis C Virus patients undergoing antiviral treatment therapy (Sovaldi medication). Quasi experimental design (one group pre/posttest) was used to achieve the aim of the study. The study was conducted in the Liver Institute at Shebin El kom District, Menoufia Governorate. A purposeful sample of 50 patients with hepatitis C virus patients undergoing antiviral treatment therapy (Sovaldi medication) from the above setting were recruited. Three instrument were used for data collection (1): Structured interview questionnaire to assess demographic and clinical data (2): Hospital anxiety and depression scale to measure emotional distress. (3): Self-efficacy scale to measure patients’ self-efficacy. The result revealed that there were statistical significant improvements of patient’s knowledge, patients’ emotional distress, liver enzymes and self-efficacy post program than preprogram. Conclusion: Nursing intervention program is the key element for management of patients’ emotional distress, self-efficacy and reduction of liver enzymes. Recommendation: psych educational program should be given for all patients with hepatitis C virus undergoing antiviral treatment therapy to improve their knowledge about the drug and promote adherence by counseling patients on the recognition and management of treatment related adverse effect. Encourage them to discuss their problem with health care team and participate in self-help program to decrease emotional distress and increase self-efficacy.

Highlights

  • Hepatitis C virus (HCV) infection continues to be an important global health problem, and is one of the main causes of chronic liver disease worldwide

  • Of the world’s population has been infected with hepatitis C virus (HCV), but most of them are unaware of their infection and more than 170 million chronic carriers who are at risk of developing liver cirrhosis and/or liver cancer [2]

  • The nurse should assess patients who suffering from significant discomforts either related to disease symptoms or treatment side effects and take immediate action to help them manage it and encourage them to discuss their problem with health care team who can prescribe medications and offer other suggestions that are effective in managing such problems

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Summary

Introduction

Hepatitis C virus (HCV) infection continues to be an important global health problem, and is one of the main causes of chronic liver disease worldwide. The long-term impact of Hepatitis C Virus infection is highly variable in Egypt, from minimal changes to extensive fibrosis and cirrhosis with or without hepatocellular carcinoma [1]. Because of the world wide prevalence of hepatitis C virus and the associated cirrhosis and mortality, treatment is an important issue which may be carried out by combination therapy of Interferon and. El. Malky et al.: The Effectiveness of Nursing Intervention Program on Emotional Distress, Self-Efficacy, and Liver Enzymes Among Hepatitis C Virus Patients Undergoing Antiviral Treatment Therapy (Sovaldi Medication)

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