Abstract

REVIEW QUESTION/OBJECTIVE The objective of the proposed systematic review is to critically analyze currently available research studies and present the best available evidence related to the effectiveness of different mosquito control strategies used in the prevention and control of chikungunya. The primary review question is: What is the effectiveness of-mosquito control strategies used in the prevention and control of chikungunya? INCLUSION CRITERIA Types of participants Countries that have reported local or imported cases of chikungunya and countries that are at risk of chikungunya due to the presence of mosquito vectors of chikungunya (including Aedes aegypti and Aedes albopictus) will be included. Types of intervention(s)/phenomena of interest Interventions of interest will be mosquito control strategies broadly classified as chemical control, biological control and/or habitat control. These strategies are specifically used to target mosquitoes that transmit chikungunya, including Aedes aegypti and Aedes albopictus. Studies that were not specific to chikungunya (e.g. entomological control measures across generic mosquito-borne diseases) were excluded. Types of outcomes The primary outcome of interest is the number of chikungunya cases or the rate of chikungunya transmissions following implementation of mosquito control strategies The secondary outcomes of interest are changes in mosquito (egg, larvae, pupae and adult stages) populations, which may be described and monitored using entomological indices including: Percentage mortality or survival rates of mosquitoes. Lethal concentrations: toxicity measure of an insecticide that will kill 50% or 90% of the mosquito sample population in a specific period of time. Knockdown time: time required to TRUNCATED AT 250 WORDS

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