Abstract
Purpose To evaluate the efficacy of laser peripheral iridotomy (LPI) in preventing deterioration in eyes with ocular hypertension (OHT) and concave configuration of the iris. Materials and Methods This was a retrospective study, which was carried out within a period of 3–5 years. Twenty-four patients with OHT and concave irises were treated with LPI and followed up periodically. IOP, central corneal thickness (CCT), anterior chamber depth (ACD), scleral spur angle (SSA), global neuroretinal rim (NRR) thickness, and global retinal nerve fiber layer (RNFL) were examined before and after LPI. Results The average age of the 24 patients was 14.21 ± 1.41 (13–17.5) years on admission. The initial IOP of the 48 eyes was 23.21 ± 1.56 mmHg in RE and 22.96 ± 2.1 mmHg in LE before LPI. All 48 eyes had concave irises in both eyes. All eyes treated with LPI have shown iris flattening, which has persisted during follow-up (mean 1.54 ± 0.9 years). At the last follow-up visit, the average IOP was 17.58 ± 2.63 (14–21) mmHg in RE and 17.58 ± 2.86 (14–21) mmHg in LE, which was statistically lower than that of the baseline (p < 0.001). There were significant changes in SSA in both eyes and global RNFL in RE after LPI. Conclusions In the current study, LPI resulted in an IOP-lowering effect and iris flattening in adolescent eyes with a concave configuration of the peripheral iris.
Highlights
To evaluate the efficacy of laser peripheral iridotomy (LPI) in preventing deterioration in eyes with ocular hypertension (OHT) and concave configuration of the iris
LPI resulted in an IOPlowering effect and iris flattening in adolescent eyes with a concave configuration of the peripheral iris
E aim of this study was to assess the effects of LPI on lowering intraocular pressure (IOP) in adolescents with OHT and concave configuration of the iris visible in anterior segment optical coherence tomography (AS-OCT)
Summary
To evaluate the efficacy of laser peripheral iridotomy (LPI) in preventing deterioration in eyes with ocular hypertension (OHT) and concave configuration of the iris. Twenty-four patients with OHT and concave irises were treated with LPI and followed up periodically. LPI resulted in an IOPlowering effect and iris flattening in adolescent eyes with a concave configuration of the peripheral iris. When IOP in patients with PDS is high or when signs of glaucomatous optic nerve develop, treatment should be initiated. E aim of this study was to assess the effects of LPI on lowering IOP in adolescents with OHT and concave configuration of the iris visible in anterior segment optical coherence tomography (AS-OCT). We assumed that peripheral iris concavity may be a risk factor for the development of PDS in adolescents, making pigment release easier. We wanted to investigate whether laser therapy results in any changes in the anterior segment parameters and in the optic disc and retinal parameters, as assessed by optical coherence tomography
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