Abstract

The ketogenic diet is one of the alternative treatment management of epilepsy patients. The study aimed to examine the effect of the ketogenic diet for managing the epilepsy patients. A literature review used by databases to find the relevant articles included Science Direct, Scopus, and Pro-Quest from 2011 to 2018. Metabolic therapy with the ketogenic diet can improve mitochondrial function, increase inhibition, and reduce nerve stimulation, which can cause seizures in epilepsy patients. Also, other factors need to be considered to produce an optimal impact on the use of the ketogenic diet, such as patient compliance and age. The ketogenic diet is one of the non-pharmacological alternatives that can be done to prevent recurrence in epilepsy patients. 
 Keywords: ketogenic diet, epilepsy, literature review

Highlights

  • Epilepsy is a transient event caused by excessive neuronal activity or inconsistency in the brain (1)

  • The study aimed to examine the effect of the ketogenic diet for managing epilepsy patients

  • A literature review used by databases to find the relevant articles included Science Direct, Scopus, and Pro-Quest from 2011 to 2018

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Summary

Introduction

Epilepsy is a transient event caused by excessive neuronal activity or inconsistency in the brain (1). Based on data from the World Health Organization (WHO), the number of people living with epilepsy currently reaches 60 million peoples with an average prevalence of active epilepsy was 8.2 per 1000 population (2). Epilepsy has an impact on the quality of life. Schachter (2016) explained that the ketogenic diet significantly impacts for epilepsy management (4). The ketogenic diet used since 1921 is a diet high in fat, moderate protein, and low in carbohydrates. This combination of energy can cause ketosis, which serves to relieve seizures (5). The ketogenic diet has attracted the attention of researchers in the last 30 years (6)

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