Abstract

To search for neurophysiological predictors of the effectiveness of rhythmic transcranial magnetic stimulation (rTMS) of the left dorsolateral prefrontal cortex in patients with depressive disorder of various nosology. Thirty-four young male patients with protracted treatment resistant depression were studied using psychopathological, psychometric methods and encephalography. A search for predictors of therapeutic efficacy was carried out in a wide range of neurophysiological indicators using different high-frequency rTMS protocols (10 Hz and 20 Hz).. The most significant changes were obtained using rTMS with a frequency of 20 Hz. A favorable effect of treatment was correlated with higher spectral power of the alpha- and beta 1-rhythm bands in EEG.

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