Abstract
The article presents data on the effectiveness of the use of a new drug developed by us for the treatment of mastitis in cats, which includes the antibacterial drug ceftriaxone and Kalanchoe leaf dust. Due to the fact that mastitis in cats is now widespread, and also causes significant damage to owners of cat catteries, the problem of inflammation of the mammary gland is a matter of concern to veterinarians. Among veterinarians, the development and search for new economically and therapeutically effective methods of treating this pathology is urgent. When conducting studies on the basis of the North Caucasian Zonal Research Veterinary Institute, it was found that therapy for feline mastitis using the antibacterial drug amoxicillin LA 15% twice with an interval of 48 hours at the rate of 1 ml of the drug per 10 kg of animal body weight, as well as the use of the developed us ointments based on the antibacterial drug ceftriaxone and Kalanchoe leaf dust twice a day for 5 days showed a high degree of effectiveness. The therapeutic efficiency of the proposed method of therapy was 100%, the recovery of the studied animals occurred on average on the 3rd day of using this method. Also, in the course of the studies, it was found that in the complex treatment of mastitis in cats using the ointment developed by us based on the antibacterial drug ceftriaxone and Kalanchoe leaf dust, as well as the antibacterial drug amoxicillin LA 15%, recovery occurs on average in 3.3 days, while the therapeutic the effect is 100%. When using only the antibacterial drug amoxicillin LA 15% twice with an interval of 48 hours at the rate of 1 ml of the drug per 10 kg of animal body weight, the duration of the therapeutic course averaged 4.7 days, which is 1.5 days more than in the experimental group. At the same time, it was also found that with mastitis in cats in the experimental and control groups, the body temperature significantly exceeds the physiological norm. After the treatment, both in the experimental and in the control group, the body temperature dropped to normal values. The parameters of the pulse and the number of respiratory movements per minute in the experimental and control groups of animals before the start of treatment exceeded the parameters of the physiological norm. After the treatment, the pulse and respiration in the studied cats were also at the upper limits of the norm. Such an excess of physiological indicators indicates a stressful state of animals, in which the number of heart beats and respiratory movements in cats increases as a result of transportation and contact with other animals and people. When analyzing these indicators of the morphological analysis of the blood picture of the studied animals, it was found that with mastitis in cats, the blood picture changes in the form of leukocytosis, an increased level of ESR. After the therapy in the experimental and control groups, the level of leukocytes and ESR decreased to normal values.
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