Abstract

BackgroundThe high demand for health care services and the growing capability of artificial intelligence have led to the development of conversational agents designed to support a variety of health-related activities, including behavior change, treatment support, health monitoring, training, triage, and screening support. Automation of these tasks could free clinicians to focus on more complex work and increase the accessibility to health care services for the public. An overarching assessment of the acceptability, usability, and effectiveness of these agents in health care is needed to collate the evidence so that future development can target areas for improvement and potential for sustainable adoption.ObjectiveThis systematic review aims to assess the effectiveness and usability of conversational agents in health care and identify the elements that users like and dislike to inform future research and development of these agents.MethodsPubMed, Medline (Ovid), EMBASE (Excerpta Medica dataBASE), CINAHL (Cumulative Index to Nursing and Allied Health Literature), Web of Science, and the Association for Computing Machinery Digital Library were systematically searched for articles published since 2008 that evaluated unconstrained natural language processing conversational agents used in health care. EndNote (version X9, Clarivate Analytics) reference management software was used for initial screening, and full-text screening was conducted by 1 reviewer. Data were extracted, and the risk of bias was assessed by one reviewer and validated by another.ResultsA total of 31 studies were selected and included a variety of conversational agents, including 14 chatbots (2 of which were voice chatbots), 6 embodied conversational agents (3 of which were interactive voice response calls, virtual patients, and speech recognition screening systems), 1 contextual question-answering agent, and 1 voice recognition triage system. Overall, the evidence reported was mostly positive or mixed. Usability and satisfaction performed well (27/30 and 26/31), and positive or mixed effectiveness was found in three-quarters of the studies (23/30). However, there were several limitations of the agents highlighted in specific qualitative feedback.ConclusionsThe studies generally reported positive or mixed evidence for the effectiveness, usability, and satisfactoriness of the conversational agents investigated, but qualitative user perceptions were more mixed. The quality of many of the studies was limited, and improved study design and reporting are necessary to more accurately evaluate the usefulness of the agents in health care and identify key areas for improvement. Further research should also analyze the cost-effectiveness, privacy, and security of the agents.International Registered Report Identifier (IRRID)RR2-10.2196/16934

Highlights

  • BackgroundConversational agents are among the many digital technologies being introduced into the health sector to address current health care challenges, such as shortages of health care providers, which reduce the availability and accessibility of health care services [1,2,3]

  • Are the conversational agents investigated effective at achieving their intended health-related outcomes, and does the effectiveness vary depending on the type of agent? Second, how do users rate the usability and satisfactoriness of the conversational agents, and what specific elements of the agents do they like and dislike? what are the current limitations and gaps in the utility of conversational agents in health care? These objectives build on previous systematic reviews while widening the scope of included studies to update the body of knowledge on conversational agents in health care and to inform future research and development

  • The reference management software EndNote was used for initial screening, with keywords based on the original search categories used to exclude studies that did not meet the criteria

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Summary

Introduction

Conversational agents use artificial intelligence (AI), including machine learning (a statistical means of training models with data so that they can make predictions based on a variety of features) and natural language processing (NLP; the ability to recognize and analyze verbal and written language) to interact with humans via speech, text, or other inputs and outputs on mobile, web-based, or audio-based platforms [1,4]. The high demand for health care services and the growing capability of artificial intelligence have led to the development of conversational agents designed to support a variety of health-related activities, including behavior change, treatment support, health monitoring, training, triage, and screening support. An overarching assessment of the acceptability, usability, and effectiveness of these agents in health care is needed to collate the evidence so that future development can target areas for improvement and potential for sustainable adoption

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