Abstract
Background and aims: The present study aimed to determine the effect of acceptance and commitment therapy on perceived stress, resilience, and the quality of life in thalassemia major patients in Lordegan during 2015-2016. Methods: This semi-experimental study used the pre-test and post-test designs with a control group and period. The samples included 40 patients with thalassemia major who referred to Lordegan Shohada hospital, were selected by the purposeful sampling technique based on the inclusion and exclusion criteria, and were randomly assigned to experimental and control groups. The experimental group received eight-week sessions of the acceptance and commitment-based therapy, while the control group received no intervention until the end of the study. The data were collected by the perceived stress questionnaire (Cohen et al), Researcher Conner and Davison Resilience Scale, and the World Health Organization Quality of Life (SF-26). Finally, the obtained data were analyzed using the SPSS software, repeated measure, and covariance tests Results: The results showed that there was a significant difference between the experimental and control groups in terms of the perceived stress, resilience, and the quality of life (P<0.001). In addition, based on the results, 66% of the changes in the perceived stress scores, 81% of the difference in the resiliency scores, and 75% of the difference in the quality of life scores were related to the impact of therapy based on the acceptance and group commitment. Further, the results of the analysis variance of the internal group revealed that the effect of therapy based on the acceptance and commitment on the perceived stress, resilience, and the quality of life had a significant difference in pretest, posttest, and follow-up stages. Conclusion: In general, the therapy based on the acceptance and commitment is found to be a useful practice in reducing the perceived stress while increasing the resilience and improving the quality of life in patients with thalassemia major.
Highlights
Thalassemia is a congenital autosomal recessive disease and an inherited hemoglobinopathy result of defection in making the globin chains, that forces the patients to regularly inject blood and replace the iron [1]
Various studies conducted in this regard indicated that therapy based on acceptance and commitment has an effect on stress [16], resilience [17], and the quality of life [18]
The inclusion criteria included the diagnosis of thalassemia major by oncology specialist, the lack of non-acute or chronic disease other than the major thalassemia, reading literacy, writing and normal IQ, satisfaction with participation in the study, obtaining unsatisfactory scores of perceived stress questionnaires by Cohen et al [19], responding to Conner and Davison [20], and the quality of life of the World Health Organization (SF26)
Summary
Thalassemia is a congenital autosomal recessive disease and an inherited hemoglobinopathy result of defection in making the globin chains, that forces the patients to regularly inject blood (for survival) and replace the iron [1]. Nowadays, the third therapeutic generation has been able to obtain the necessary validation to be posed as a replacement for behavioral cognitive therapies that emphasized experimental and basic features in the psycho-cognitive experiences These therapies seek to increase the relationship between the individual psychocognitive behavior to his feelings and thoughts instead of changing the cognition. The present study aimed to determine the effect of acceptance and commitment therapy on perceived stress, resilience, and the quality of life in thalassemia major patients in Lordegan during 2015-2016. Conclusion: In general, the therapy based on the acceptance and commitment is found to be a useful practice in reducing the perceived stress while increasing the resilience and improving the quality of life in patients with thalassemia major.
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